Agenda - OPCI Nashville 2026 Clinical Mastery Summit

7:30 – 7:35 AM
Welcome & Why Are We Here

7:35 – 7:40 AM
Opening Survey & Pre-Assessment

7:40 – 8:15 AM
SESSION I — CT-Guided PCI: Planning the Complex Case

7:40 – 7:46 AM
CT-Guided PCI — What It Is and Why It Changes the Game
7:46 – 7:52 AM
Building a Successful CT-Guided PCI Program — Key Ingredients and Institutional Requirements
7:52 – 7:58 AM
What Good Looks Like — Imaging Standards, Workflow Integration, and Real-World Benchmarks
7:58 – 8:03 AM
CT-Guided PCI in Action — Informed Planning, Lab Execution, and Outcome
8:03 – 8:15 AM
Discussion — What Does It Take to Start Planning on CT?

8:15 – 9:15 AM
SESSION II — Physiology-Guided PCI: From the Epicardial Lesion to the Microvasculature

8:15 – 8:20 AM
Wire-Based vs. Angio-Derived Physiology — Knowing When to Use What
8:20 – 8:25 AM
Discussion — Wire or Angio-Derived: Where Is the Line?
8:25 - 8:45 AM
Technology Showcase: Same Case, Different Workflows
- 8:25 – 8:28 AM
  Platform Review: Medtronic CathWorks FFRangio
- 8:28 – 8:31 AM
  Platform Review: Medis QFR
- 8:31 – 8:34 AM
  Platform Review: Pie Medical / Siemens vFFR
- 8:34 – 8:37 AM
  Platform Review: Philips Spectrawave X1
- 8:37 – 8:45 AM
  Discussion — Same Case, Four Numbers: Did They Agree?
8:45 - 9:15 AM
CMD In-Focus
- 8:45 – 8:55 AM
  In Focus: CMD in Practice — From Suspicion to Diagnosis to Treatment
- 8:55 – 9:05 AM
  Lecture: What Good Looks Like — Building and Running a CMD Program
- 9:05 – 9:15 AM
  Discussion — Starting a CMD Program: What Stops You?

9:15 – 10:10 AM
HANDS-ON ROTATION 1

9:15 – 10:10 AM
Group 1: Room A | Plan Before You Cross — CT & Angiography-Derived Physiology (3 tables, 15 min each)
9:15 – 10:10 AM
Group 2: Room B | See the Vessel — OCT-Based Imaging (3 tables, 15 min each)
9:15 – 10:10 AM
Group 3: Room C | Guide & Treat at the Table — IVUS-Integrated Workflows & Complex PCI Tools (3 tables, 15 min each)

10:10 – 10:25 AM
BREAK

10:25 – 11:05 AM
SESSION III — From Rock to Result: A Playbook for Calcium

10:25 – 10:30 AM
Know Your Enemy: Understanding Calcium and What the Evidence Tells Us
10:30 – 10:35 AM
Discussion — Assess Before You Treat: When Do You Modify?
10:35 - 11:10 AM
The Calcium Toolbelt: Mechanisms of Modification
- 10:35 – 10:38 AM
  Fracture: Intravascular Lithotripsy
- 10:38 – 10:41 AM
  Ablation: Orbital Atherectomy
- 10:41 – 10:44 AM
  Ablation: Rotational Atherectomy
- 10:44 – 10:47 AM
  Focal Force: Cutting & Scoring Balloons
- 10:47 – 10:50 AM
  Brute Force: Very-High-Pressure Balloons
- 10:50 – 10:57 AM
  Discussion — What to Use When
- 10:57 – 11:05 AM
  In Focus: Tough Decisions in Calcium — Calcified Nodules and How to Treat Them
- 11:05 – 11:10 AM
  Discussion — The Nodule: Which Tool, and What Result Do You Accept?

11:10 AM – 12:10 PM
LUNCH & SYMPOSIUM
Sponsored by Abiomed

12:10 PM – 1:05 PM
HANDS-ON ROTATION 2

12:10 PM – 1:05 PM
Group 2: Room A — Plan Before You Cross — CT & Angiography-Derived Physiology (3 tables, 15 min each)
12:10 PM – 1:05 PM
Group 3: Room B — See the Vessel — OCT-Based Imaging (3 tables, 15 min each)
12:10 PM – 1:05 PM
Group 1: Room C — Guide & Treat at the Table — IVUS-Integrated Workflows & Complex PCI Tools (3 tables, 15 min each)

1:05 – 2:05 PM
SESSION IV — When Stents Fail: The ISR Playbook — Diagnose the Mechanism, Know the Tools, Optimize the Result

Part 1 — Diagnose the Mechanism

1:05 – 1:10 PM
Why Stents Fail — ISR Mechanisms and Types
1:10 – 1:18 PM
Imaging Is the Gold Standard — The Platform Landscape and What Is Optimal for What
1:18 – 1:25 PM
Discussion — Mechanism First: What Would You Image, and With What?

Part 2 — Know Your Tools: What We Have to Treat ISR

1:25 – 1:28 PM
Balloon-Based Preparation in ISR — Scoring, Cutting, and Very-High-Pressure
1:28 – 1:31 PM
Laser Atherectomy in ISR — Mechanism, Technique, and What the Data Say
1:31 – 1:34 PM
Lithotripsy and Atherectomy for the Underexpanded Stent
1:34 – 1:37 PM
Repeat Drug-Eluting Stent — When a New Layer Is the Right Answer
1:37 – 1:40 PM
Brachytherapy — Where It Still Fits
1:40 – 1:50 PM
Discussion — What to Use When

Part 3 — Optimize the Result: Diagnose, Treat, Verify

1:50 – 1:58 PM
Case: What good looks like — From Mechanism to Endpoint
1:58 – 2:05 PM
Discussion — Diagnose, Treat, Verify: When Are You Done?

2:05 – 3:00 PM
SESSION V — DCB Frontiers: Scaffold-Free Strategies & What's Coming Next

2:05 – 2:10 PM
DCB Evidence, Approved Indications & Off-Label Practice
2:10 – 2:15 PM
Paclitaxel vs. Limus: Mechanism, Data Review, and Clinical Implications
2:15 – 2:20 PM
Discussion — The Verdict: Which Drug, and How Far Off-Label?
2:20 – 3:00 PM
Scenario-Based Decisions: What Is the Same, Which Strategy Wins
- 2:20 – 2:23 PM
  Scenario 1: Neointimal Hyperplasia — Does the DCB Win?
- 2:23 – 2:28 PM
  Discussion — Neointima: Is the DCB the Default?
- 2:28 – 2:31 PM
  Scenario 2: Underexpanded Stent — Is There Any Role for a DCB?
- 2:31 – 2:36 PM
  Discussion — Underexpansion: Fix It First, Then What?
- 2:36 – 2:39 PM
  Scenario 3: Diffuse or Multilayer ISR — DCB, DES, Brachytherapy, or Surgery?
- 2:39 – 2:44 PM
  Discussion — Multilayer ISR: When Do You Stop Stenting?
- 2:44 – 2:50 PM
  In Focus: Leave Nothing Behind — Where Scaffold-Free PCI Is Heading, and the Signs It's Already Here
- 2:50 – 2:53 PM
  Case: A Bioresorbable Scaffold for In-Stent Restenosis — Would You Have Done It?
- 2:53 – 3:00 PM
  Discussion — Out of the Box: Expanded Uses in Practice, and the Devices on the Horizon

3:00 – 3:55 PM
HANDS-ON ROTATION 3

3:00 – 3:55 PM
Group 3: Room A | Plan Before You Cross — CT & Angiography-Derived Physiology (3 tables, 15 min each)
3:00 – 3:55 PM
Group 1: Room B | See the Vessel — OCT-Based Imaging (3 tables, 15 min each)
3:00 – 3:55 PM
Group 2: Room C | Guide & Treat at the Table — IVUS-Integrated Workflows & Complex PCI Tools (3 tables, 15 min each)

3:55 – 4:05 PM
BREAK

4:05 – 4:25 PM
SESSION VI — Complex Situations and Complication Management

4:05 – 4:08 PM
Case 1
4:08 – 4:15 PM
Discussion
4:15 – 4:18 PM
Case 2
4:18 – 4:25 PM
Discussion

4:25 – 4:30 PM
WRAP-UP & CLOSING | Final Assessment & Post-Survey

5:15 PM
END & NETWORKING RECEPTION